Get Antibiotic resistance : causes and risk factors, mechanisms PDF

By Adriel R. Bonilla

ISBN-10: 1607416239

ISBN-13: 9781607416234

ISBN-10: 1607419734

ISBN-13: 9781607419730

ISBN-10: 1616681624

ISBN-13: 9781616681623

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2000). , 1996). The authors postulated that the active component responsible for the antimicrobial property was a low molecular weight substance produced by the probiotic strain. This substance can inhibit the growth of MRSA. , short-chain fatty acids) could decrease the density of the pathogenic strains. Acetic acid and lactic acids could lower the colonic pH and favor the growth of less pathogenic organisms. The exact mechanisms by which probiotics limit the spread of antibiotic resistance are diverse and often strain-dependent.

Becoming resistant to an antibiotic and proliferating under the selective pressure of that agent (Tenover, 2006). The presence of accessory genetic elements such as transposons and plasmids, in addition to chromosomes in the bacteria genome, greatly increases the potential for the spread of the resistance gene. This is especially true if the gene is carried by a mobile genetic element or is itself a self-transferable plasmid or transposon (Courvalin, 2006). , 1999). Vancomycin resistance in enterococci such as E.

Acetic acid and lactic acids could lower the colonic pH and favor the growth of less pathogenic organisms. The exact mechanisms by which probiotics limit the spread of antibiotic resistance are diverse and often strain-dependent. Although in vitro studies have demonstrated that probiotics could prevent and treat antibiotic resistance, more studies must be performed to determine the efficacy of probiotics in vivo. However, in vivo trials can be variable due to the variation and complexity of the intestinal microbiota between different mammals.

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Antibiotic resistance : causes and risk factors, mechanisms and alternatives by Adriel R. Bonilla


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